Agmatinase belongs to the family of. Agmatinase enzyme hydrolyze agmatine into urea and putrescine, which belong to one of the pathways producing polyamines, essential for cell proliferation. Agmatine amidinohydrolase, or agmatinase, catalyzes the conversion of agmatine to putrescine and urea.
Agmatinase is an enzyme specifically responsible for the catabolism of agmatine, playing a critical role in the brain. It catalyzes the conversion of agmatine into urea and. Here, it may serve two different functions, the.
Agmatinase is thought to be expressed in multiple brain regions, however it may not contribute to polyamine production from arginine (via agmatine) in mammals since the expression of. Agmatine has received considerable attention as a potential neurotransmitter and the human enzyme so far annotated as agmatinase (agmat) has been proposed as an. Agmatinase (ec 3.5.3.11) belongs to the arginase (see arg1, 608313) superfamily of enzymes and hydrolyzes agmatine to putrescine and urea. This enzyme is found broadly across kingdoms of life and plays a critical role in.
This activity downregulates the biologic.